Ultradilution

2012

Identification of Medicinally Active Ingredient in Ultradiluted Digitalis purpurea: Fluorescence Spectroscopic and Cyclic-Voltammetric Study.

Sharma A, Purkait B.

J Anal Methods Chem. 2012;2012:109058.

ABSTRACT: Various concentrations of serially diluted and agitated Digitalis purpurea commercially available were analyzed using cyclic voltammetry, emission spectroscopy, and UV-VIS spectroscopy. These analytical methods apparently identified the medicinal ingredients in commercial homeopathic preparation of the drugs.

 

Multiweek resting EEG cordance change patterns from repeated olfactory activation with two constitutionally salient homeopathic remedies in healthy young adults.

Bell IR, Howerter A, Jackson N, Brooks AJ, Schwartz GE.

J Altern Complement Med. 2012 May;18(5):445-53.

ABSTRACT: The study evaluates effects of different homeopathic remedies on resting electroencephalography (EEG) cordance after an olfactory activation on healthy young adults. Given previous evidence of correlations between EEG cordance and single-photon emission computed tomography (PET), the data showed significant interactions of remedy and cordance variations, controlling for gender and chemical sensitivity.

 

Therapeutic Effect of Arsenicum album on Leukocytes.

Ive EC, Couchman IM, Reddy L.

Int J Mol Sci. 2012;13(3):3979-87.

ABSTRACT: The study confirms the protection of a continuous cell line (the MT4 cells) against the toxic effects of the arsenic trioxide (As2O3) by the homoeopathic remedy Arsenicum album. The results showed that the potencies 30CH and 200CH, had effects on cells and confirmed that different potencies have different effects. The study also showed that succussion does not cause changes in the effects. Therefore a biotechnological method could be used to evaluate the effects of homoeopathic remedies on human cells.

 

Potential of the homeopathic remedy, Arnica Montana 30C, to reduce DNA damage in Escherichia coli exposed to ultraviolet irradiation through up-regulation of nucleotide excision repair genes.

Das S, Saha SK, De A, Das D, Khuda-Bukhsh AR.

Zhong Xi Yi Jie He Xue Bao. 2012 Mar;10(3):337-46.

ABSTRACT: Arnica Montana 30C helped repair the DNA damage in E.coli through up-regulation of repair genes and also ameliorated the oxidative stress through the reduction of intracellular reactive oxygen species generation and suitable modulation of anti-oxidative stress enzymes.

 

Potentiated homeopathic drug Arsenicum Album 30C inhibits intracellular reactive oxygen species generation and up-regulates expression of arsenic resistance gene in arsenite-exposed bacteria Escherichia coli.

De A, Das D, Dutta S, Chakraborty D, Boujedaini N, Khuda-Bukhsh AR.

Zhong Xi Yi Jie He Xue Bao. 2012 Feb;10(2):210-27.

ABSTRACT: The study shows that Ars Alb 30C administration reduced arsenic toxicity and DNA damage in E. coli by inhibiting intracellular reactive oxygen species generation and increasing tolerance to arsenite toxicity and cell growth.

 

2011

An Exploratory Study on Scientific Investigations in Homeopathy Using Medical Analyzer

Nirupama Mishra, K. Charan Muraleedharan, Akalpita Sriniwas Paranjpe, Devendra Kumar Munta, Hari Singh, and Chaturbhuja Nayak. The Journal of Alternative and Complementary Medicine. August 2011

ABSTRACT

Background: The action of homeopathic medicines, in ultra-high dilution, is not directly observable. An attempt was made to explore autonomic response of selective homeopathic medicines, in healthy persons, using Medical Analyzer System (Electronics Division, Bhabha Atomic Research Centre, Mumbai, India).

Objective: The objective of the study was to observe the action of homeopathic medicines on physiologic variability of heart rate and blood flow.

Material and methods: Pre- and postinterventional variability spectra of heart rate and blood flow of 77 subjects were recorded with the Medical Analyzer System, administering homeopathic preparations of Aconitum napellus (6c, 10M), Arsenicum album (200c, 1M), Gelsemium sempervirens (200c, 1M), Phosphorus (200c, 1M), Pulsatilla nigricans (200c) and Sulphur (200c, 1M) versus placebo control. The amplitude of the peaks viz. low-frequency, medium-frequency, and high-frequency was measured for postintervention analysis. An increase in the amplitude of any valid peak by 100% or a decrease by 50% was considered as significant change.

Results: Aconitum napellus produced a response in heart rate variability (HRV) with 30c potency and in blood flow variability with 1M potency. Sulphur 200c and 1M, Gelsemium 200c and Pulsatilla 200c, produced a 62.5% response in HRV against the placebo response of 16.6%. Gelsemium, Phosphorus, and Sulphur produced a response in blood flow variability with a 1M potency, similar to the response of Aconitum napellus 1M.

Conclusions: These data suggest that it is possible to record the response of homeopathic medicines on physiologic parameters of the autonomic nervous system.

 

2009

Domains of Water Molecules Provide Mechanism of Potentization in Homeopathy

Czerlinski G, Ypma T.

Department of Biology, Western Washington University, Bellingham, WA 98225

Department of Mathematics, Western Washington University, Bellingham, WA 98225

In homeopathy, high potentization means such high dilution that there is no longer even one molecule of the original active agent per gram of the mixture. Nevertheless such high dilutions apparently remain effective. We develop a possible mechanism for homeopathic potentization to explain this phenomenon. This mechanism consists of three consecutive processes: initiation, multiplication, and amplification. Initiation is the mechano-chemical generation, by strong shaking following each dilution step, of radicals which remain in existence by mutual stabilization in simultaneously formed electronic domains. Multiplication transfers electronic excitation level structures from the original homeopathic agent to these radical-containing domains, stabilizing them further. These stabilized domains participate in the multiplication process until all the domains contain the critical information. Amplification is the generation of the same number of information-containing domains as existed prior to dilution. This amplification step can be repeated any number of times, with the original agent eventually diluted to negligible levels but the information-containing component regenerated to the same concentration in each step. In our first model we assume each domain is contained in a separate water cluster. In an alternative mechanism we consider two domains contained within one water cluster, altering the initiation process. The equations derived from these mechanisms are linked to observables (indicators) and may be used to obtain precise numbers for rate constants and concentrations from future experiments, some of which are outlined.

 

 HIGH DILUTION EFFECT REPORTED IN NMR STUDY

Reference:? Demangeat J-L (2009) NMR water proton relaxation in unheated and heated ultrahigh aqueous dilutions of histamine: Evidence for an air-dependent supramolecular organization of water. Journal of Molecular Liquids, 144:32-39

A new study in the Journal of Molecular Liquids by Jean-Louis Demangeat at the Nuclear Medicine Department of the General Hospital in Haguenau, France reports physical modifications in the solvent of ultrahigh aqueous dilutions of histamine.

 

 

2008

Electrical impedance and HV plasma images of high dilutions of sodium chloride.

Assumpção R.

Homeopathy. 2008 Jul;97(3):129-33.

ABSTRACT: Author reports impedance data and high voltage plasma photographic plates of an homeopathic up to 30 CH dilution of sodium chloride. Results clearly differ from ‘pure’ water

 

Delayed luminescence of high homeopathic potencies on sugar globuli.

Lenger K, Bajpai RP, Drexel M.

Homeopathy. 2008 Jul;97(3):134-40.

ABSTRACT: Delayed luminescence signals of Homeopathic remedies absorbed onto sugar globuli was observed by exciting them at their known resonance frequency. Results can be considered as indicative of holistic quantum structures in homeopathic potencies.

 

Lipid peroxidation, erythrocyte antioxidants and plasma antioxidants in osteoarthritis before and after homeopathic treatment.

Pinto S, Rao AV, Rao A.

Homeopathy. 2008 Oct;97(4):185-9.

ABSTRACT: The study attempts to evaluate the status of oxidative stress in osteoarthritis (OA), by measuring some parameters of oxidant stress and antioxidant defenses in blood, before and after homeopathy treatment. On homeopathic treatment the lipid peroxidation  has decreased in the erythrocytes, which shows and reduced oxidative stress.

 

A nuclear magnetic resonance spectroscopy comparison of 3C trituration derived and 4C trituration derived remedies.

Botha I, Ross AH.

Homeopathy. 2008 Oct;97(4):196-201

ABSTRACT: This study sought to establish whether the claim that C4-derived potencies possess different physicochemical qualities to the homoeopathic medicines derived from a 3cH trituration is valid.

Five different samples were analysed using Nuclear Magnetic Resonance (NMR) Spectroscopy.

Authors show a significant difference between the 12cH samples of potassium dichromate (Kalium bichromicum) produced from 3cH and 4cH triturations.

Trituration seems to play a part in the development of physicochemical properties specific to homoeopathic medicines.

 

Nonlinear dynamical systems effects of homeopathic remedies on multiscale entropy and correlation dimension of slow wave sleep EEG in young adults with histories of coffee-induced insomnia.

Bell IR, Howerter A, Jackson N, Aickin M, Bootzin RR, Brooks AJ.

Homeopathy. 2012 Jul;101(3):182-92.

ABSTRACT: The study findings of remedy-related sleep stage alterations in human subjects by testing the feasibility of using two different nonlinear dynamical systems (NDS) analytic approaches to assess remedy effects on human slow wave sleep electroencephalographic (EEG). Homeopathic medicines Coffea cruda and Nux vomica in 30c potencies alter short-term nonlinear dynamic parameters of slow wave sleep EEG in healthy young adults.