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Kaolin and pectin (KAY-oh-lin and PEK-tin) combination medicine is used to treat diarrhea.
Kaolin is a clay-like powder believed to work by attracting and holding onto the bacteria or germ that may be causing the diarrhea.
Kaolin and pectin are administered together to serve as an adsorbent and protectant. Kaolin is a natural hydrated
aluminum silicate that is believed to adsorb large numbers of bacteria and toxins and reduce water loss. Pectin is a
polyuronic polymer for which the mechanism of action is unknown. Pectin consists of purified carbohydrate
extracted from citrus fruit or apple pomace. Studies have shown no decrease in stool frequency or fecal weight and
water content with this combination even though stools appeared more formed. Kaolin and pectin are both not
absorbed following oral administration (up to 90% of pectin is decomposed in gastrointestinal tract).
Kaolin, due to the aluminum in its compositon, may lower the bioavailability of other ingested medications. Taking
doses of other oral medications 2 to 3 hours before or after doses of kaolin pectin is not recommended.