Substances & Homeopatic Remedies

Mancinella venenata

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hippomane mancinella L.


manzana, apple, from Old Spanish
Latin (mla) Matina, (apples) of Matius, possibly after Caius Matius Calvena (fl. first century b.c.), Roman author of a cookbook.
Hippo - horse


Traditional name

Poison Guava  

Used parts

Tincture of fruit, leaves and bark.


Plantae; Spermatophyta, Angiospermae - Flowering Plants; Dicotyledonae; Rosiflorae / Rosidae; Euphorbiales; Euphorbiaceae - Spurge Family


Original proving

Manc. was introduced into homeopathy by Bute, who proved it. It was also proved by Mure and Ackermann.

Description of the substance

Also called Poison Guava  (Hippomane mancinella), tree of the genus Hippomane, of the spurge family (Euphorbiaceae), that is famous for its poisonous fruits. The manchineel is native mostly to sandy beaches of the Caribbean and Gulf of Mexico. Its attractive, single or paired yellow-to-reddish, sweet-scented, applelike fruits have poisoned Spanish conquistadores, shipwrecked sailors etc.

MANCHINEEL.-The Hippomane Mancinelli, Linné, a West Indian tree possesses poisonous properties. Its fruit, resembling in color and size our common apple, is said to poison fish when placed in the water. The tree abounds in acrid, milky juice, the poisonous principle of which is volatile. Fat, resin, caoutchouc, volatile oil, gummy material, and mancinellin are, according to Ricord-Madianna, constituents of manchineel. The juice of the tree is highly irritating, causing vesication, and if in contact with the conjunctiva, producing a violent conjunctivitis. The Indians poison arrows with it; even sleeping underneath the tree is said to produce swelling of the body. Both the juice and the fruit produce inflammatory gastro-intestinal symptoms, with emeto-catharsis.

 Description: A tree, 6 to 15 m hight much branched with thick necked twigs. Leaves shiny green, stalked, with elliptical edges cut like saw - teeth, a single gland on upper side where the stalk and leaf join; Flowers very small inconspicuous, on long slender spikes, females placed singly at base, males in little clusters, on the upper part with a two parted calyx and two or four stamens joined by their filaments; ovary, many celled crowned with 4 to 8 styles and reflex stigmas. Fruit a berry, rounded, fleshy, yellow green.