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The biotoxicity of crude and fractionated extracts of A. aurita from the Caribbean waters, showed Stinging Haemolytic and Neurotoxic activity.
The moonjelly is harmless for humans. The threadlike tentacles around the edge of the bell can sting, and may occasionally catch small swimming animals for food, but their stings - like minute harpoons fired by springs - are not powerful enough to pierce the human thick skin.
Although Moon jellies are relatively harmless, skin irritation can result if the animals are handled. The jellyfish can cause low amounts of dermatotoxicity.