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Constituents: See USDA plant chemicals, reference works
Use of M. pudica in Medicine
The seeds and other parts of M. pudica contain mimosine, a non-protein alpha-amino acid that is known to cause hair loss and depressed growth in mammals. However, an unlikely large dose would be necessary to cause such problems in humans.
Extracts of the plant have been shown in scientific trials to be a moderate diuretic, depress duodenal contractions similar to atropine sulphone, promote regeneration of nerves, and reduce menorrhagia. Antidepressant activity has been demonstrated in humans. Root extracts are reported to be a strong emetic, due to the mimosine.
Although the plant is used in herbal medicine, especially the Indian Healthcare System known as Ayurveda, it is not yet used in mainstream medicine; and pharmaceutical companies are still researching its properties and uses.
The aqueous root extract of Mimosa pudica dose dependently inhibited the hyaluronidase and protease activities of Indian snakes (Naja naja, Vipera russelii and Echis carinatus) venom.
The decoction of Mimosa pudica leaves given intraperitoneally at dose of 1000-4000 mg/kg protected mice against pentylentetrazol and strychnine-induced seizures. M. pudica had no effect against picrotoxin-induced seizures It also antagonized N-methyl-D-aspartate- induced turning behavior. These properties could explain its use in African traditional medicine
Ethanolic extract of Mimosa pudica leaves given by oral route to mice at a dose of 250 mg/kg showed a significant hyperglycemic effect.
There might be a potential role for mimosa pudica in treating strongyloides stercoralis infections and against vibrio cholerae