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Proteus mirabilis Hauser 1885AL (Bacteria)
Proteus mirabilis Swarm
The attenuations of This nosode are prepared from the sterilized filtrate obtained from rinsing off cultures of bacterium proteus)
Animalia; Chordata / Vertebrata - Vertebrates; Mammalia - Mammals; Nosodes
Proteus spp.: Proteus mirabilis, Proteus vulgaris
We owe to F. Sevaux, a study of clinical pathogenesis (see above) in Cahiers de Biotherapie, No.8, December, 1965.
Description of the substance
E' un batterio che provoca putrefazione. Agente putrefattivo che si trova nella carne putrida, ascessi, processi suppurativi. Si trova nelle vie urinarie in infezioni gravi.
The genus Proteus is classified in the enteric bacteria,(Gram-negative bacteria), together with Escherichia coli, Salmonella, Shigella, Enterobacter and Serratia. All these bacteria are small, Gram-negative rods and are facultative anaerobes: they ferment sugars in anaerobic conditions but can use a wide range of organic molecules in aerobic conditions.
P. mirabilis are small bacilli about 1 µm in length, is also well-known for its ability to swarm over the surface of agar media,. When these cells contact a surface, they can change into elongated, highly flagellated cells commonly 20 - 30 µm long. These swarmer cells secrete a polysaccharide slime, arrange themselves into rafts parallel cells and then move rapidly over the solid surfaces.
Proteus has two interesting and notable features.:First, Proteus is unique, however, because it is highly motile and does not form regular colonies. Instead, the cells are highly motile and often swarm across the surface of agar plates. Swarming gives rise to a very thin film of bacteria on the agar surface, but swarming periods are interspersed with periods when the cells stop and undergo a cycle of growth and division so that the colony has a distinct zonation. The other notable feature of both Proteus is the ability to degrade urea to ammonia, by production of the enzyme urease.
Found in soil, water, sewage, decomposing matter and human intestinal tract. Hydrogen sulfide production O, H, K antigens: grouping on basis of these antigens for epidemiologic studies have not been correlative. Share antigens with the intracellular pathogen Rickettsia.
Proteus, like almost every other bacterium in this family, can cause urinary tract infections and
hospital-acquired infections. The most important member of this genus is considered to be P.mirabilis, a cause of wound and urinary tract infections. Fortunately, most strains of P. Unlike its relative, P. vulgaris is not sensitive to these antibiotics.