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---Medicinal Action and Uses---Vermifuge and vermin-destroying. Stavesacre seeds are extremely poisonous and are only used as a parasiticide to kill pediculi, chiefly in the form of the official ointment, the expressed oil, the powdered seeds, or an acid aqueous extract containing the alkaloids.
These seeds are so violently emetic and cathartic that they are rarely given internally, though the powdered seeds have been given as a purge for dropsy, in very small quantities at first and increased till the effect is produced. The dose at first should not exceed 2 or 3 grains, given in powder or decoction, but the administration of the drug must always be accompanied by great caution, as staphisagrine paralyses the motor nerves like curare.
The seeds are used as an external application to some cutaneous eruptions, the decoction, applied with a linen rag, being effectual in curing the itch. It is made by boiling the seeds in water.
Delphinine has also been employed similarly to aconite, both internally and externally, for neuralgia. It resembles aconite in causing slowness of pulse and respiration, paralysis of the spinal cord and death from asphyxia. By depressing the action of the spinal cord it arrests the convulsions caused by strychnine.