Substances & Homeopatic Remedies

Zincum sulphuricum

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INTERACTIONS:
Zinc is a very important mineral, which is responsable for many functions in animals as well as plants. Zinc deficiencies can provoke many different problems. The replacement of zinc is offered in pharmaceutical preparations as zinc sulfate or zinc orotate. It is not known whether zinc sulfate will harm an unborn baby. Taking zinc with foods high in calcium or phosphorus may decrease the absorption of zinc. Zinc sulfate may decrease the absorption of a great variety of antibiotics.

CASUAL INTAKE, OVERDOSE and POISONING:
Abdomen, GI-Tract:
As zinc sulfate may hydrolyze into acid if swallowed, severe irritation and burns of the mouth, throat and digestive system may occur. Symptoms may include nausea, vomiting, dehydration, stomach pain, diarrhea, kidney damage, hemorrhagic pancreatitis, and other gastrointestinal disturbances. A fatality following ingestion of 10 grams has been reported. Lethal dose: Zinc Sulfate, 7-Hydrate: Oral rat LD50: 2150 mg/kg. Zinc sulfate anhydrate: oral rat LD50: 1710 mg/kg.
Nervous system:
Chronic exposure may cause fatigue, slow tendon reflexes, central nervous system depression, tremors, restlessness, paralysis of the extremities, headache, drowsiness, increased sweating, and also hallucinations.
Lungs, Inhalation:
Inhalation causes irritation to the respiratory tract, coughing and shortness of breath.
Skin:
Skin Contact causes irritation to skin, redness, itching, and pain.
Eyes:
Eye concact may provoke redness, pain and temporary loss of vision.
Blood:
High zinc doses can lower the HDL cholesterol and raise the LDL cholesterol.
Zinc acts as a critical ingredient to immune cell function, assisting in cell division and growth. And as a component in thymic hormone, zinc serves to control the maturation of Iymphocytes.
Taste and Smell: (also see to chapter History)
Zinc sulfate has a very special relationship to taste and smell in different ways.
Zinc sulfate inhibits the sweetness of 12 chemically diverse sweeteners (glucose, fructose, aspartame, saccharin, sorbitol, etc.) in a concentration dependent manner. Curiously, zinc sulfate does not inhibit the sweetness of Na-cyclamate.
Zinc activates areas of the brain that receive and process information from taste and smell sensors. Its importance to appetite was first demonstrated in 1972 when researchers showed taste disorders responded to zinc supplementation.
There is no ethical scientific way to experiment with intranasal zinc to see what actually happens in human adults due to the severity of the zinc-anosmia reaction. Judging from the reports of others, the damage in adults appears to last many months or years, and is likely to be life-long in duration.
In uncontrolled clinical trials, the administration of oral zinc sulfate has been reported both to prevent and correct taste abnormalities in cancer patients receiving external radiotherapy (ERT) to the head and neck region. Patients receiving zinc sulfate had a quicker recovery of taste acuity than those receiving placebo.

DEFICIENCY:
Zinc is one of the essential elements for plant and animal life. In plants, it serves as a growth hormone and influences protein synthesis. Zinc deficiency causes stunting of the plant, yellowing of the leaves and decreased yields of seed, grain, vegetables or fruit.
Zinc deficiency in animals was not recognized until 1934. Today we understand the importance of zinc in maintaining normal health and increased  yields, especially in swine and poultry. In swine, a lack of zinc in the diet causes  parakeratosis, characterized by dermatitis, diarrhea, vomiting, decreased appetite, severe  weight loss and eventual death. In poultry, zinc deficiency results in loss of appetite,  growth retardation, blood disorders, arthritic deformities, bone diseases and death. Zinc  supplements to the diet often cause prompt recovery. Zinc Sulfate is the optimum source of  zinc in animal feeds as the nutritional source of zinc due to its biological availability.
There is evidence that zinc deficiency is implicated in deteriorating vision that comes with aging or poor night vision.
Thin peeling off fingernails.
Chronic diarrhea, inflammatory bowel disease, diabetes, alcoholism, pancreatic  disorders, and kidney disease may indicate a need for a zinc supplement.
Some conditions may increase your need for zinc. These include:
Acrodermatitis enteropathica (a lack of absorption of zinc from the intestine), alcoholism,burns, diabetes mellitus, Down's syndrome, eating disorders, gastrectomy, intestine diseases, infections (chronic), kidney, liver, and pancreatic diseases, sickle cell disease, skin disorders, stress (chronic), thalassemia, trauma (prolonged). In addition, premature infants may need additional zinc.

ZINC SULFATE SOURCES IN FOOD
Food sources  include: Brewer's yeast, eggs, kelp, lamb, lima beans, liver,  meat, pecans, whole grains, oysters (best source), and shellfish. The body  absorbs up to 40% of zinc from food eaten.

VETERINARY MEDICINE
Ovine foot rot is a contagious disease of sheep that causes severe lameness. It is caused by an interaction of two anaerobic, Gram (-) bacteria, Bacteroides nodosus (formerly Fusiformis nodosus) and Fusobacterium necrophorum (formerly Sphaerophorus necrophorus). Zinc sulfate baths for the hoof is perhaps the most effective and least toxic therapy.

MEDICINE
Zinc sulfate is used (as a gel 1 or 1%) for herpes simplex infections of the skin. It has an antiviral and adstringent effect. Zinc ions adhere to the membrane of herpes virus and thus impede the adherence of the virus to the host cell and the intrusion of the virus to the cell.
Zinc sulfate can also be an ingredient of tooth pastes, together with sodium fluoride, with the aim to reduce plaques and caries.
Zinc in brain tissue stimulates mental activity. Zinc, found in vesicles of the mossy fiber system of the brain's hippocampus, interacts with other chemicals to send messages to the sensory brain center, enhancing memory and thinking skills.
Researchers found that women deficient in zinc had a harder time on standard memory tests. Other scientists found lower cognition in men experimentally deprived of zinc.
In many elderly individuals, immunity decreases, making them more susceptible to disease. Providing adequate zinc-and a balanced diet-has been shown to help decrease their rate of infectious diseases.
Zinc is essential for healthy skin. Zinc is a natural sun screen, protecting chapped lips and skin from the sun's rays. Zinc sulfate is effective in treating some cases of acne. In a water-based solution, zinc sulfate helps remedy cold sores. Zinc also improves healing of wounds, like surgical incisions, burns and other skin irritations. Used as an anti-inflammatory, zinc soothes skin and skin tissue. Poison ivy, sunburn, blisters and gum disease are all improved when treated with zinc. Zinc is even a natural insect repellent. Zinc stimulates the transport of Vitamin A from the liver to the skin, helping to protect body tissue from damage.


Its importance to appetite was first demonstrated in the early 1970s when researchers showed taste disorders responded to zinc supplementation. Since that time, researchers and physicians are finding that zinc is a sustaining factor in abnormal eating behavior.
Several studies have suggested that there may be a correlation of zinc deficiency and pathophysiology of ADHD. Zinc is involved in the production and modulation of melatonin, and therefore is also considered to be a factor in ADHD.
This new double blind and placebo controlled trial shows the Parent and Teacher Rating Scale scores improved with zinc sulfate over a 6-week period.

Many researchers have demonstrated the critical role of zinc (Zn) in diverse physiological processes, such as growth and development, maintenance and priming of the immune system, and tissue repair. Exposure to ionizing total-body radiation suppresses hematopoiesis, resulting in decreased production of blood cells. The aim of the clinical study was to determine the effects of zinc sulfate on early hematopoietic toxicity, caused by total-body irradiation of rats  There was significantly increased white blood cell count, when compared with control group.
It would be worthwhile studying the effect of oral zinc sulfate supplements in radiation-treated cancer patients, in the hope of reducing radiation-induced toxicity.
Zinc has  been found to be comparable to Vitamin C, Vitamin E, and beta-carotene in antioxidant qualities.

The results of a study to investigate a possible effecte of zinc in the treatment of warts indicate that oral zinc sulfate is effective in the treatment of chronic viral warts.
Zinc reduces the body’s ability to utilize the essential mineral copper. (For healthy people, this interference is circumvented by supplementing with copper, along with zinc.) The ability to interfere with copper makes zinc an important therapeutic tool for people with Wilson’s disease.

Zinc is an essential mineral for the growth and function of the reproductive organs. The prostate gland in men contains an abundance of zinc.
A deficiency may present the following symptoms: delayed sexual maturation, fatigue, hair loss, and impotence.
Zinc sulfate may have an influence on infertility. If zinc sulfate is administered in combination with folic acid the number of spermatocyts will almost be double. The administration of only either one of the two substances has no result. Probably zinc sulfate promotes the intestinal resorption of folic acid.